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Of the stimuli used in this study, αIgM treatment had the strongest effects on gene expression in vitro and was capable to activate a wide range of signalling pathways.
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In contrast, both sc-tPA and tc-tPA are capable to activate epidermal growth factor receptors (EGFRs), a mechanism mediating the antiapoptotic effects of tPA.
In addition, TGFβ is capable to activate other, non-Smad intracellular pathways.
Once a helper T cell has been activated by an antigen, it becomes capable of activating a B cell that has already encountered the same antigen.
For decades, medical experts have underestimated the versatility of microbes, which are capable of activating a set of genes and thereby creating resistance in hours or days.
PAMPs are a group of molecules that are capable of activating a wide array of innate immune defenses.
Furthermore, urothelium may protect the basal cells from toxins or other substances capable of activating a pathological cell growth.
We first tested whether the mutant GATA3 from MCF7 cells (mutGATA3) was capable of activating a target gene.
Thus, ghrelin is clearly capable of acting as a hormone to activate the GH axis at the hypothalamic level.
Taken together, we had four strong AIs capable of activating transcription to within a factor of two of α-factor (AI-Ste4p, AI-Ste11p, AI-Ste7p, AI-Ste12p), one moderately weak AI (AI-Ste5p), and two weak AIs (AI-Ste2p, AI-Fus3p).
A gene capable, when activated, of transforming a cell.
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