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Collectively, miR-200c-3p miR-200c-3p miR-200c-3pandble miR-141-3p miR-141-3p miR-141-3pACE2 protein and have a critical role during H5N1 virus infection.
microRNAs (miRNAs) are approximately 21 nt transcripts capable of regulating the expression of many mRNAs and are abundant in the brain.
This so-called "epithelial-mesenchymal transition program" relies on a number of powerful transcription factors, which are stimulated by factors in the tumour cell environment and are capable of regulating the expression of the molecules that drive invasion and metastasis.
And the DAM methylase gene is capable of regulating the expression of other genes, including multidrug efflux pumps.
Taken together, these findings suggest that resveratrol and DHEA are capable of regulating the expression of TXNIP and Sirt1, however in a tissue-specific manner.
HR-HPV E6 oncoprotein through the degradation of p53 [ 92] is capable of regulating the expression of numerous coding and noncoding genes including miRNAs [ 14].
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Methylation and demethylation reactions at specific histone lysine methylation marks, regulated by a combination of specific methyltransferases and demethylases, are capable of regulating the expression levels of different proteins involved in controlling cellular homeostasis.
Specifically, in CD4+ T lymphocytes and macrophages the role of several microRNAs (miRNAs) capable to regulate the expression of the Cyclin T1 subunit has been recently elucidated.
We have shown that dietary γ-tocopherol, but not α-tocopherol, is capable of down regulating the expression of the fecal ras- p21 gene.
Moreover, the miRNAs themselves are capable of controlling DNA methylation and histone modification by regulating the expression of genes that govern these epigenetic pathways.
They lie in non-coding regions and probably act by regulating the expression of nearby genes.
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