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Pituitary adenomas (PA) are histologically benign tumors of the sella that are capable of recurrence following resection.
Most cases are reported from eastern Asia and although their biological behaviour has not been fully investigated these neoplastic IPT are, at least, capable of recurrence and metastasis.
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Adenosarcomas generally are low-grade neoplasms capable of local recurrence after polypectomy or hysterectomy and less commonly distant metastasis.
These findings should be taken into consideration when counseling the patients on the most effective therapies capable of avoiding recurrence of clinical disease, pain, and associated infertility.
The length of time for the survival rate to plateau in breast cancer might indicate the involvement of a cell type capable of disease recurrence which is able to withstand primary treatment and reside in the body, often undetected, for prolonged periods.
However, one can conceptually speculate that a certain subset of cancer cells with stem like properties is not affected by cytoreductive treatment, might evolve by clonal evolution, might systematically acquire de novo genetic alterations and might become capable of effecting recurrence.
These markers may pinpoint quiescent MM cells capable of fueling recurrences.
We conclude that Bz-surviving MM cells display a GRP78HIGH/p21HIGH/CDK6LOW/P-RbLOW profile, and these markers may identify quiescent MM cells capable of fueling recurrences.
The present study reports the transfer of two multigene signatures (Buck-14, IR-7) capable of predicting metastatic recurrence risk for HRneg/Tneg breast cancers from microarray-based gene expression profiles on fresh/frozen tumor samples to an RT-PCR assay platform suitable for use with FFPE tumor samples.
Of noninvasive diagnostic methods FDG-PET scans are among the few options capable of identifying early recurrences or secondary tumor occurrence [ 11].
Rather the purpose was to adjust for the therapy administered to patients in order to have a model capable of generating predictions of recurrence-free survival on the basis of prognostic factors only.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com