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According to Aulehla and Herrmann, this would define the boundary between cells that are still capable of oscillation and cells in which the oscillations have been arrested.
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Formerly, we demonstrated in three chemical systems how the combination of the shrinking response of an appropriate responsive gel and a pH-switch type chemical reaction, which is not capable of oscillations by itself, can lead to self-oscillations in size and in pH in a piece of gel surrounded by a constant environment.
These results suggest that we have evolved an autonomous oscillator capable of sustained oscillations in the absence of an environmental stimulus.
The control is designed by extending the logic of SMA and integrating it with the LMI technique to develop a single-gain feedback controller that is capable of damping oscillations in large systems.
System (4) is capable of producing oscillations due to the reciprocal connections between the two populations.
This is an example of a module where the strong nonlinear negative feedback is capable of generating oscillations.
It is interesting to note that three pairs of conjugate-complex eigenvalues were observed for the Jacobian matrix, which suggests that the system is capable of damped oscillations.
Similarly, Montagne et al. have combined templates, primers, DNA polymerase, a nicking enzyme, and an exonuclease to create a nucleic acid circuit capable of sustained oscillations.
Neurons have a rich repertoire of ionic currents capable of subthreshold oscillations that can store the information about the arrival of an IPSP for periods of time much greater than the duration of the initial perturbation.
The model demonstrates for the first time that the UPR is capable of generating oscillations in translation attenuation and the apoptotic signals, and this is supplemented with a Bayesian sensitivity analysis identifying a set of parameters controlling this behaviour.
Accordingly, insertion of 2-gene repression-based synthetic loops in bacteria indeed may give rise to bistable dynamics [ 8], whereas 3-gene repression-based synthetic loops inserted into living bacteria are capable of spontaneous oscillations with a very long period (more than 2.5 hours, i.e. twice the cell doubling time) [ 9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com