Exact(6)
Gene transfer into pancreatic cells in vivo could be of immense therapeutic benefit in cases of type 1 diabetes (T1D) through the production of molecules capable of interrupting the progression of autoimmunity or promoting regeneration of insulin-secreting β cells.
Small interfering RNA (siRNA) molecules are capable of interrupting the translation of a specific protein by inducing post-transcriptional gene silencing.
Tumor growth could be inhibited by fenofibrate as this drug is capable of interrupting the systemic changes in lipid metabolism such as hypertriglyceridemia and hypercholesterolemia in B-cell tumor-bearing mice.
On the other hand, core decompression that was originally performed as a diagnostic procedure has been advocated as a technique capable of interrupting the disease process when performed before subchondral collapse.
As evinced by the PPI-deficient CypB mutants, the development of pharmacophores capable of interrupting the intranuclear transport and/or function of these polypeptides may provide highly effective agents capable of inhibiting the hormone/growth factor-driven proliferation and progression of breast malignancies.
The development of 5-LO Xinhibitors capable of interrupting the 5-lipoxygenase axis in prostate cancer cells remains the focus of numerous investigations, and there is increasing evidence suggesting that LOX inhibition is a promising therapeutic approach in the treatment of prostate cancer [ 13, 14].
Similar(54)
My research intends to develop small molecules capable of interrupting this feedback loop in order to study its contribution to cancer initiation and maintenance.
Here we investigate the consequences of interrupting the elongation process.
These natural antioxidants have been shown to have access to metabolic processes and are capable of interrupting free radical-mediated reactions by donating hydrogen from the phenolic hydroxyl groups to free radicals [8].
In these experiments, lignocaine at a dosage of 10 μg (capable of interrupting stimulus-induced responses to either electrical stimulation of the dura mater or mechanical stimulation of the craniofacial skin) reduced basal the discharge rate of second-order trigeminovascular neurons.
Many of the factors that have made 2003 a difficult year to sell ad space -- from the uncertain economy to the unstable Middle East to the unsettling surge in demand for a competing medium, television -- continue to loom large and are capable of interrupting any songs in celebration of September or coming months.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com