This is the first documented hospital-wide outbreak of VREG and highlights the fact that uncommon species of enterococci are capable of nosocomial dissemination.
Interventions need to not only be successful but to also be capable of wide dissemination and implementation at reasonable cost.
Thus, an important area of future optimization involves the development of fluorescent dyes capable of greater dissemination among the tissues of live worms.
In a study from Vietnam disease caused by the Euro-American lineage was significantly more likely to be pulmonary than meningeal, which suggests that this lineage is less capable of extrapulmonary dissemination in this population [ 49].
Nonetheless, ILBCs are capable of widespread metastatic dissemination.
Although cancer vaccines are generally considered safe, vaccines incorporating autologous tumor carry a risk of implanting tumor cells that are capable of growth and dissemination in the patient.
Drugs that target this stage could be capable of blocking the dissemination and thus prevent rapid life threatening progression of the infection.
In reality, only a small minority of tumor cells in the primary tumor is actually motile and capable of invasion and dissemination at any given time, as has been visualized in mouse and rat mammary tumor models with intravital multiphoton microscopy [ 8, 9].
SpeB activates host proteins through cleavage, such as interleukin-1β precursor and pro-matrix metalloprotease-2 and -9; these mature forms are capable of aiding in GAS dissemination from the site of infection through increased inflammation and tissue damage, respectively [17], [19].
Large wind events are capable of global-scale transport and dissemination of PM and microbes.
