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Indeed, the comparison of the natural ligands exhibiting several-fold preference, in terms of relative affinity, for the PSD95-PDZ2 dovern over the PSD95-PDZ1 domain with the best binders of the latter clearly suggests that these domains are also capable of differential recognition (Fig. 5B).
With this end in mind, we designed and deployed a multifaceted phage display screening strategy to identify peptide motifs capable of differential binding to Integra® matrices.
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Vannevar Bush's first differential analyzer: This machine was capable of solving differential equations mechanically — a milestone in the development of modern analytical machines.
With Clifford Berry, he developed the Atanasoff-Berry Computer (1937 42), a machine capable of solving differential equations using binary arithmetic.
This data base, although small, strongly indicates that mouse models can sort the diagnostic symptoms of autism, and suggests that biological and physiological analyses of these strains may be capable of providing differential information on the brain systems involved in particular symptoms of this disorder.
It is also capable of the differential diagnosis of both rinderpest and PPR antigens.
One factor capable of causing differential evolutionary divergence between paralogs is natural selection.
Nevertheless, the constructed model must be capable of producing differential expression in the different territories to qualify as a model of development.
These time courses do not reproduce experimental time courses, but they demonstrate that our provisional model is capable of producing differential expression.
Existing tools, such as the Sashimi plot provided within the MISO package (Katz et al., 2013), are capable of showing differential splicing between individual samples, but not between genotypes (a three-way comparison).
Since generally rarer, 5' end polymorphic isomiRs may represent a significant proportion of the population of some miRNAs we investigated in vitro whether 5' isomiR of miR-140-3p miR-140-3p miR-140-3pindeed capable of conferring differential targeting recognition and thus has different functions in the porcine luminal endometrium.
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