Moreover, work from budding yeast has shown that a complex containing only the Mcm4 and 7 subunits is specifically capable of unwinding DNA [ 25], and biochemical analysis of the corresponding Mcm4/7 ATPase active site demonstrates that it is particularly important for both steady-state ATP hydrolysis and DNA unwinding activities of the Mcm2-7 hexamer [ 19, 23, 24].
Capable of holding up to 30 gallons of water, the machines were specifically designed to absorb water at the National Tennis Center.
Moreover, the C-terminal domains of Bxb1 and TnpX have been shown previously to be capable of binding specifically to DNA [25], [41], [42].
The plasma membranes of various kinds of cells have been recently shown to be capable of binding specifically and with a high affinity to SHBG, mediating sex hormone signaling at the cell membrane through SHBG receptors [ 7, 8].
EMSA analysis was performed to test whether YY1 is capable of binding specifically to such recognition motifs present in the Plp1 gene.
TILs have been shown to be capable of specifically eliminating tumour cells (Aebersold et al, 1991), but also to be rendered potentially nonfunctional due to tumour-induced immunosuppression (Finke et al, 1990).
The effect of DA was, therefore, activity dependent, demonstrating that the reinforcing signal is capable of acting specifically on the active inputs.
The unicellular green alga Chlamydomonas reinhardtii is capable of acclimating specifically to singlet oxygen stress, but the retrograde signaling pathway from the chloroplast to the nucleus mediating this response is unknown.
This combination was reported to be capable of specifically delivering the vaccines to the draining lymph nodes and preferentially activating the medullary macrophages (Muraoka et al., 2014), which resulted in effective cross-priming of vaccine specific effector T cells and anti-tumor activities in murine colon cancer and sarcoma models.
