We have adapted the VAS and the COVAS use for ratings of itch perception and have demonstrated that these scales are 1) sensitive to manipulations which can reduce itch, 2) capable of assessing changes in itch intensity over time, and 3) able to distinguish differences between acute and chronic itch [20], [21].
Experimental results indicate that PA is indeed capable of assessing changes that occur during the aggregation process for the two types of RBCs used in these experiments.
Importantly, to our knowledge, the GRCD is the only ObsRO for RSV disease developed in accordance with the FDA PRO guidance recommendations for use in clinical trials incorporating feedback from the population of interest and capable of assessing change after treatment in a standardized manner and supporting an understanding of treatment benefit for novel RSV therapies.
In the future, when the present method is employed together with some quantitative methods, such as SILAC, iTRAQ or label-free quantification methods, it will be capable of assessing the changes in protein expression and these two PTMs in one analysis, which reduces the inter-experimental variations in the quantitation.
In longitudinal studies, quantitative MRI (qMRI) has been found to be capable of precisely and reliably assessing changes in cartilage volume/thickness over time [ 11- 21].
While a CGE model is capable of assessing structural and technological change effects of policy shocks, this study argues that it is important to study short-run consequences for the purpose of developing mitigation strategies as unwillingness to encounter additional costs usually impedes necessary policy reforms.
The work in this paper bridges this gap by describing the development and application of IMPACT (integrated model for population ageing consequences on transportation), a GIS-based PSS capable of assessing the ramifications of demographic changes, including population ageing, on the performance and usage of urban transportation systems.
By considering the aforementioned ontological changes to anatomy, physiology, and biochemistry, pediatric PBPK models capable of assessing the impact of growth and maturation on drug PK can be developed.
Moreover, no study has purposely evaluated or been capable of assessing trends in the incidence and outcome of AKI in critically ill patients over time, once changes in illness severity have been taken into account [ 21].
Each cell culture is capable of assessing the toxicity of a different chemical.
Information entropy is capable of assessing feature randomness and content.
