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These sequence aligners are capable of aligning billions of reads (stored as fasta or fastq files) on reference genome in few minutes.
This general scheme has been exemplified in virtually every spliced alignment method capable of aligning a cDNA against a whole genomic assembly.
Barnacle's fusion sensitivity improves when read support is recalculated using read-to-contig alignments generated by ABySS-map, which is capable of aligning parts of reads to short sequences and the edges of sequences (Additional file 1: Table S2, rows 2 and 4).
Thus, the recent MSA programs [ 18, 20] capable of aligning large quantities of 16S rRNA sequences must be evaluated for their alignment accuracy, as currently performed for Muscle, T-COFFEE, MAFFT, Probcons, and the Clustalw MSA programs for protein sequences [ 25, 26].
Because ECM is a kind of cellular adherent molecules, ECM-patterned cell culture surface is capable of aligning cells on the pattern of ECM.
Currents of this magnitude are capable of aligning collagen fibrils as they aggregate from the solution phase and are known also to alter the cell-based development of regeneration buds in amphibia.
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In cases where blastn was not capable of unambiguously aligning the terminal edges of exons, absolute intron size was calculated using the genomic distance between aligned neighboring HSPs.
In this situation, given the recent success of the generalized dual-bootstrap iterative closest point (GDB-ICP) [26] which is capable of successfully aligning a pair of images starting from just one correct correspondence [50], the UR-SIFT-PIIFD can provide the initial matches for the GDB-ICP algorithm and may register images successfully.
Based on these two experiments, we conclude that the MSA programs tested are capable of accurately aligning the reliable sequences, even in the presence of a large proportion of sequences with discrepancies.
However, we did not find any algorithm or tool capable of exhaustively aligning more than 2 or 3 non-redundant clan AA families (and in all cases the automated alignment needed manual refinement).
The preferred data format for files submitted to the SRA is the BAM format, which is capable of storing both aligned and unaligned reads.
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