Even though we did not quantify the viability of osteoblasts derived from transplanted cells, we presume that these differentiated, rather than un-differentiated cells, have more capability to differentiate into the osteoblasts and calcify.
It is expected that any measurement procedure has the capability to differentiate between pathological and normal performance.
Bone marrow stromal cells (BMSCs) play a crucial homeostatic role in skeletal modeling and remodeling due to their capability to differentiate into osteooblasts.
The signal processing and feature extraction are done using discrete wavelet transform due to its capability to differentiate between high and low frequency transient components.
In this study, we determined whether the BMDMSCs from patients with osteoarthritis could maintain their capability to differentiate into chondrocytes in the presence or absence of b-FGF in culture medium.
Spatial resolution of the MUVE technique was found to be approximately 200 μm, while detection sensitivity, defined as the capability to differentiate between materials based on mechanical property differences, was approximately 0.2 kPa using agarose hydrogels.
This study suggested that with optimum in vitro manipulation, PLGA/fibrin when seeded with pluripotent non-committed BMSCs has the capability to differentiate into chondrogenic lineage and may serve as a prospective construct to be developed as functional tissue engineered cartilage.
Mesenchymal stem cells (MSCs) have the capability to differentiate into a variety of connective tissue cells including bone, cartilage, tendon, muscle, and adipose tissue (Pittenger et al. 1999).
Therefore, DUD-E provides an excellent dataset for benchmarking docking algorithms and scoring functions to help objectively evaluate the capability to differentiate between active and decoy compounds, which is critical for a reliable compound ranking in virtual screening.
