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In addition, the capability of migration and invasion decreased significantly.
The capability of migration of SKOV3 cells treated with control siRNA or Fli-1 siRNA were also examined.
The capability of migration of MSCs may be mediated by increased chemokines such as SDF-1 in surrounding environment and CXCR4 presented on MSCs [ 141].
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Local control of the tumor is difficult in more than 80% of cases, because glioma cells infiltrate the surrounding tissues with high capabilities of migration and invasion.
To further investigate this, we isolated liver ECs from WT and CD146EC-KO mice and compared their capabilities of migration and tube formation in vitro.
And LnM1-S11 exhibited stronger capabilities of migration than other cell lines, except of LM1-S4 (p <0.0001; Fig. 3b).
The results revealed that the hybrids of GES-1 and CM-MSCs undergo epithelial-mesenchymal transition (EMT), indicated by the increased capability of proliferation, migration and invasion, and the expression of EMT-related genes and tumor formation in nude mice.
However, persons with sufficientcapacities to aspire and realise migration may never decide to migrate, while theabsence of the capability for migration makes voluntarily migration very unlikely.
In general, the capability for migration can be thought of as a necessary condition fora person to be considered a potential migrant.
The capability of tumor cell migration was assessed using a wound-healing assay.
Upregulation of PTEN resulted in the inhibition of migration capability of glioma cells under in vitro conditions.
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