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The degree of aggregation, however, is not only dependent on the ionic strength; different cations clearly show a different capability of binding to the polymers.
In vitro binding data showed that, compared to the original mAbs, the modified mAbs (S-mAbs) had greater capability of binding two TNF molecules simultaneously.
Accordingly immunological assessment of the humoral immune response should include not only the determination of antigen specific antibody level but also the capability of binding to effector cells.
The layer-by-layer self-assembly of SL can also easily be produced in saline solution because of its capability of binding transition metal ions such as Cu2+ and Zn2+.
The high redox property of CeO2, which is also called as oxygen storage capacity (OSC), originates from the capability of binding O2 reversibly by shifting from Ce3+ to Ce4+ states under oxygen-rich and oxygen-lean environments, respectively [3, 6].
QoS-aware dynamic binding of composite services provides the capability of binding each service invocation in a composition to a service chosen among a set of functionally equivalent ones to achieve a QoS goal, for example minimizing the response time while limiting the price under a maximum value.
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Relative to the known residues with direct contacting DNA operates, this hydrophobic amino acid of tryptophan at the position 60 of FadR regulatory protein represent a new functional residue in that it is without close contact to its cognate DNA, but required for capability of DNA binding.
To address imatinib resistance issue in CML, new-generation inhibitors, such as dasatinib, nilotinib, and ponatinib, were developed to suppress the enzyme with a capability of potently binding its active conformation [ 7].
The capability of covalent binding to DNA to predict the initiating potential of chemical carcinogens was compared for the assays performed in vivo (rodent liver DNA) and in vitro (purified DNA incubated in the presence of mouse and rat liver microsomes).
These differences between MOE and Maestro protonation for these residues contribute to a difference in hydrogen bonding capabilities of the binding site.
Theoretical DFT calculations were used to explain metal binding capability of tpmc ligand and the binding sequences were found to follow the order: Cu2+ ≫ Ni2+ > Co2+ > Zn2+.
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