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It should also be noted that a simple measure of ATM protein expression by IHC cannot establish the functional capability of ATM within the tumor.
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About 40% of ATM transactions are done at third-party machines, RateCity.com.au says.
This acetylation of ATM within its regulatory domain is essential for activating ATM's kinase activity.
ATM is a widespread architecture and it is natural to extend the two-level connection architecture of ATM to the three-level connection architecture of optical-ATM networks.
Performance of ATM networks depends on switch performance and architecture.
"Think about the introduction of ATM machines," she says.
We next studied activation of ATM and its target proteins.
Levels of ATM, p-ATM and p-Chk2 (ATM substrate) were further examined to validate knockdown or inactivation of ATM function.
Acetylation of ATM by the acetyltransferase Tip60 is required for complete activation of ATM [ 56, 57].
GC = gas chromatography (measured value, % of atm); IR = infrared values (measured value, % of atm).
For ATM inhibition, 13 μM of ATM kinase inhibitor (Calbiochem, San Diego, CA, USA) was used.
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