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Improving the reprogramming efficiency and accelerating the speed is just one aspect of using small molecule cocktails --rather than retroviruses--for reprogramming.
Open image in new window Figure 2 A large-scale screen for reprogramming regulators using OKS/pFind1 and identification of gene's capacity to cellular reprogramming.
Both PpCSP1 and Lin28 are dispensable for reprogramming and function to enhance the reprogramming.
Our TMP reprogramming system is useful for defining the stoichiometry and temporal requirements of transcription factors for reprogramming.
A few of the youngsters are shipped out to what amounts to a camp for reprogramming.
The third to fifth gametophore leaves from the apex were used for reprogramming analysis.
An easy method for reprogramming adult cells may resolve ethical objections.
A CRISPR/Cas9-based system for reprogramming cell lineage specification.
Moreover, although telomerase reactivation is necessary for reprogramming, ALT-dependent mechanism is also involved in reprogramming, in a non-sufficient way (Wang et al., 2012).
The methodology for reprogramming of somatic cells into iPSCs with defined reprogramming factors (Oct4, Sox2, cMyc and Klf4) was established by Yamanaka's group in 2006[49].
Young women who came to school with them were sometimes taken into closed rooms for reprogramming.
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