The main difference of FLCs with conventional rule-based controllers is their capability to trigger several rules simultaneously, which leads to smoother control actions.
While at short time scales, each earthquake has a magnitude-dependent ability to trigger further events, at longer time scales the capability to trigger other earthquakes appears to be independent by the magnitude (a2 = 0).
In contrast, HEK293-TLR2 and HEK293-TLR5 cells were highly competent for inducing the secretion of IL-8 and TNF-α cytokines in a cagPAI-independent manner, suggesting that the expression of TLR-2 or TLR-5 has profoundly changed the capability to trigger pro-inflammatory signalling upon infection.
Thus, the fd antigen delivery system combines the safety and capability to trigger a strong cellular antigen-specific immune response even in the absence of adjuvants.
Pioneer TFs have the unique capability to trigger cellular reprogramming while chromatin remodeling was shown to be an early bottleneck of this process [ 31– 33] (reviewed in [ 24, 34, 141]).
TNF receptors are characterized by a conserved cysteine-rich domain (CRD) that is present in one to six copies in their extracellular domain With the exception of a few soluble or GPI-anchored decoy receptors, all TNF receptors are single spanning transmembrane receptors that have the capability to trigger proinflammatory signaling pathways.
The most important properties of IgG1 are its ability to bind virtually any desired antigen with high affinity and specificity, its long in vivo half life mediated by the interaction with the neonatal Fc receptor (FcRn) and the capability to trigger immunological clearance mechanisms.
The complete inability of the Met2S receptor to execute an axonal branching decision, which contrasts with its capability to trigger MN survival, indicates that Src family kinase activation is inadequate for axonal branching by HGF/Met (or that Src antagonises the response otherwise mediated through another pathway such as PI3K; see below).
The capability of TFs to trigger trans-differentiation was initially unveiled by Davis et al. More recently, the Wernig group demonstrated that mesoderm cells (e.g., fibroblasts) can be directly converted into functional neurons.
This finding discloses the capability of LGALS3BP to trigger a humoral immune response in cancer patients and provides the basis for further investigation on a possible use of anti-LGALS3BP antibodies as biomarkers for early diagnosis of cancer.
