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These patients are more likely to have chronic comorbid conditions, which places them in higher risk CAP group, in contrast to the target CAP population of our study.
A novel series of N-hydroxybenzamide derivatives containing indole cap group was designed and synthesized.
"In the small cap group I like Affiliated Computer, Burr-Brown and Vantive Corp.," Morris says.
We show that all synthesized compounds, with varies modifications of the rigid cap group, were selective and potent HDAC6 inhibitors.
When times are bad, the small cap group gets hammered, enabling investors to buy at bargain prices.
The shift I've made now is trying not to get too over-weighted in one cap group.
Today the $480 million (market cap) group is one of the largest health care chains in Asia.
In this new class of analogs, we inserted an ethylene moiety in the linker and used indole as a part of the Y-shaped cap group.
A novel series of tripeptidomimetics with spiro ring containing sulfur atoms as cap group and linear carbochain as linker was designed and synthesized as HDACs inhibitors.
Thus, γ-lactam analogues with methoxy, trifluoromethyl groups of ortho-, meta-, para-positions of cap group were prepared and evaluated their biological potency.
In the present study, we reported the design and synthesis of a series of novel HDAC inhibitors using various substituted quinoline rings as the cap group.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com