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Herein, we used the clinical data from all patients with CAP enrolled in the multicenter ProHOSP study [ 12].
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More than 2,000 patients with clinically and radiographically diagnosed CAP were enrolled in this study.
All patients who were aged ≥18 years and admitted for severe CAP were enrolled.
From October 2010 to September 2011, adults and adolescent patients (≥ 14 years of age) with radiographically confirmed CAP were enrolled consecutively.
Nine hundred and twenty-five CAP patients enrolled in the ProHOSP trial [ 3] were analyzed by assessing clinical severity scores (SMART-COP, PSI, CURB65) and biomarker levels (PCT, MR-ProADM, Pro-ET1).
For the study on coarse and fine CAPs, we enrolled 50 participants.
From August to November 2012, 229 CAP patients were enrolled.
In total, 138 NHAP and 307 CAP patients were enrolled.
Overall, 3874 CAP patients were enrolled in our population-based clinical registry.
267 CAP patients were enrolled consecutively over our 3-year prospective study.
However, it is important to note that the CAP trials only enrolled patients who were not critically ill [ 77, 78].
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