Sentence examples for cap defect from inspiring English sources

The intensity ratio of the disorder-induced Raman D-band to the G′-band scales inversely with length, consistent with predominately end cap defect sites.

CSF leakage is considered to occur in relation to the neural canal defect, and such neural canal defects are also associated with the size of the skull cap defect into meningoencephalocele and meningocele.

That is because the replication fork struggles to reach the end of the chromosome in mrc1Δ mutants where a telomere capping defect is observed.

In budding yeast, loss of Ku causes a short telomere phenotype, as discussed above, but also a temperature-sensitive telomere-capping defect.

This difference most likely reflects the fact that cdc13-1 mrc1Δ exo1Δ mutants have more severe telomere capping defect than cdc13-1 exo1Δ mutands and therefore activate a stronger checkpoint signal.

Grandin and Charbonneau first identified STN1 as a partial suppressor of the capping defect of cdc13-1 and later identified TEN1 as a suppressor of a similar defect in STN1-mutated cells (Grandin et al, 1997, 2001).

They later showed that loss of Cdc13 function leads to massive, unregulated 5′ end resection of telomeres (Garvik et al, 1995), commonly referred to now as a telomere capping defect.

Cells with telomere capping defects containing MRC1 or mrc1 AQ, a checkpoint defective allele, exhibit similar growth, suggesting growth defects of cdc13-1 mrc1Δ are not due to checkpoint defects.

This demonstrates that Exo1-Myc is functional in the context of telomere capping defects.

We conclude that Exo1 is phosphorylated in response to different types of telomere capping defects in budding yeast.

Loss-of-function phenotypes of HipHop and K81 are typical of telomere capping defects, i.e., telomere fusion and chromatin bridges at anaphase.