The measured PSDFs offer comprehensive, canonical data sets useful for testing models of soot formation.
The canonical sequence data sets comprised 672 sequences for histone H3, 357 sequences for histone H4, 518 sequences for histone H2B, and 435 sequences for histone H2A.
These analyses identified the most statistically significant biological functions or canonical pathways in the data set.
Nonetheless, two canonical pathways in our data set may be important for CSF pressure regulation (i.e. upregulated aldosterone signaling) and CPE sink action (i.e. downregulated glutathione-mediated detoxification).
This first network is linked to the Nrf2-mediated oxidative stress pathway (one of the top scoring canonical pathways in our data set shown in Figure 4B) via the MAFF node.
One of the tools in IPA enables us to identify the enrichment of genes in selected canonical pathways from the input data set.
Associations between protein groups in the data set and canonical pathways were measured similarly to the over-representation analysis described for the microarray data above.
> -wrap-foot> Although 118 of the 120 derived introns in the combined data set contain canonical GT … AG splicing sites, two had atypical splice sites.
Using only completely sequenced species, the final histone sequence data set included canonical sequences for 160 species from plants, fungi, protozoa, and animals, with genome sizes ranging from 8 to 5600 Mbp.
We investigated the presence of TEs or remnants of TEs in the retrogenes UTRs and in their 2 kb upstream and downstream regions, and compared them with the same regions of the whole data set of "canonical" (non-retroposed) genes reported in FlyBase (Table 1).
Ap-value calculated using Fisher's exact test determining the probability that association between genes in the data set and canonical pathway is due to chance alone Cluster 1 - One hour post infestation Cluster 1 represents the immediate early (IE) group of genes with peak expression at 1 hpi.
