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It is clear that capacity-efficient schemes such as Zhang's cannot survive to signal distortions.
In Drosophila and Mus however, Syt1 null mutants are indeed lethal as they cannot survive to reproduce as adults.
Both alleles lead to severe phenotypes such that homozygous or compound heterozygous males are completely sterile and homozygous or compound heterozygous females cannot survive to reproductive age in absence of treatment.
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When administered orally, Bifidobacteria cannot survive exposure to gastric juice before they reach the intestine.
It should be underlined that cells with high intracellular TetA amounts at steady state cannot survive due to the membrane collapse.
According to this hypothesis, stem cells cannot survive long enough to function as SSCs outside of the basal compartment niche.
The ice gives it a safe platform to hunt seals and the seals it hunts cannot survive without ice to build dens for their pups.
Rex Ryan cannot survive what happened to his New York Jets on Thanksgiving night.
Because rack1a-1 rack1b-2 rack1c-1 triple mutants cannot survive in soil to maturity, they are maintained in plants homozygous for the rack1b-2 and rack1c-1 loci and heterozygous for the rack1a-1 locus.
The latter requires energy to be exported from the cell and results in a potentially toxic acidic microenvironment since most mammalian cells cannot survive prolonged exposure to an extracellular pH lower than 7.2.
In this study, we provide evidence of impaired mitochondrial metabolism in a peroxisomal disease, as fibroblasts in patients with X-linked adrenoleukodystrophy cannot survive when forced to rely on mitochondrial energy production, i.e. on incubation in galactose.
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