However, such a bias cannot explain the observed risk estimates since the ascertainment of exposure was based on the same procedure in cases and controls (interviewing parents during their child's hospitalisation).
However, any potential underreporting of diabetes and hypertension in the Danish National Registry of Patients would provide underestimates of the absolute risks, and thus cannot explain the increased risks.
Importantly, these limitations apply to all antidepressants, and cannot explain the differential mortality risk observed with paroxetine treatment.
While E2's effect on serotonin could account for the immediate increase in risk, it cannot explain the long-term reduction in risk, which is likely related to other changes associated with parturition or lactation.
But, the inefficiency of poverty as a single variable cannot explain the status of malaria risk in a country or a region properly.
We cannot explain the small increase in risk for Bell's palsy seen in this study.
Others have recognised that insulin levels per se cannot explain the disparity in the observed risk between obesity and premenopausal and postmenopausal breast cancer risk, whereas oestrogen concentrations are well correlated (Key, 2001).
This feeding strategy did not materially increase lifespan, so this cannot explain the observed increase in cancer risk.
In addition, existence of differences in terms of social contacts cannot explain the apparent difference in spatial risk between herds located in zone 2 and zone 1, where the identical spatial trend was observed.
While the macrovascular complications in patients with type 2 diabetes mellitus can partly be attributed to the increased prevalence of classic cardiovascular risk factors such as dyslipidaemia, these risk factors cannot explain the increased prevalence of atherosclerosis in type 1 diabetes mellitus [ 1– 3].
