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Although they perform with significant accuracy, this performance nevertheless remained insufficient to dispel the common fear that they are "black-boxes" whose functioning cannot be well understood and, consequently, whose recommendations cannot be trusted [ 6].
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In this context, the ligand location or protein binding geometry cannot be considered to be well understood, with many possible conformations of the same ligand plausible [6, 11].
Ultimately, protein interactions that are well understood cannot only be inhibited but also used to engineer desired cellular outcomes.
Finally, despite every attempt to ensure clarity of the questionnaire (pilot testing), it cannot be ascertained that all questions were well understood by nurses; especially among those with lower levels of education.
Although cardiac hypertrophy acts as a protective mechanism, it is well understood that this phenotype cannot be maintained long-term.
Any monitoring of global soil change cannot be successful unless soil data availability and characterization at the national level are well understood.
However, application of lignin derivatives to produce added value products cannot be realized unless the corresponding lignin recovery yield and chemistry under these pretreatment conditions are well understood.
"It is well understood by those knowledgeable about open-source software that because MySQL is open source, it cannot be controlled by anyone".
This dynamic is well understood.
It's well understood.
Superficially, its mechanism is well understood.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com