As the described DNA methylation changes in our study were identified in blood samples, an important question that cannot be directly addressed by our data is the issue of whether parallel changes occur in brain.
We cannot allow our differences over abortion to derail health care reform because, as important as the issue of abortion is, it cannot be allowed to be the issue that prevents millions of families from finally getting insured.
If so, the issue of temporality in explanations cannot be reduced to the issue of temporality in a mechanism.
In fact, differential risk does exist, and it cannot be separated from the issue of the relative aggressiveness of the bacterium.
The upshot is that it is now known that "the N.S.A. cannot be trusted on the issue of cyber security," said Soghoian.
These experiments support a possible pathogenic effect of anti-Pr3 antibodies but cannot be considered definitive, because of the issue of immune complex deposition following splenocyte transfer.
Citing the cratering public confidence in Chicago in the police force, Boykin said that "trust in the Chicago police department cannot be restored unless the issue of Homan Square is immediately, directly and decisively confronted".
A group of Iowa pro-life activists are urging Republican caucusgoers to support anyone other than Donald Trump tonight, saying in a public statement that he "cannot be trusted" on the issue of "defending unborn children and protecting women from the violence of abortion".
"If Republicans cannot be constructive on the issue of immigration, Latino voters will not listen to our candidates when they address other issues," said Alfonso Aguilar, head of the American Principles Project's Latino Partnership, a conservative Hispanic grassroots organization.
Reducing the cost of housing benefit cannot be an issue that a serious opposition shies away from: indeed, a rising housing benefit bill is far from progressive.
He told Miliband not to allow his campaign to tip over into anti-business sentiment or scalp-hunting.Some senior Labour figures believe popular opinion cannot be assuaged on the issue of bankers bonuses and it may prove necessary for Labour to set out clear principles.
