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These results point to a specific role of the non-catalytic Cik1 head that cannot be simply replaced by a second catalytically active or inactive Kar3 head.
Importantly, we found that the activity of DSNX3 in Wg secretion cannot be simply replaced by overexpression of DSNX1 or DSNX6, further demonstrating that the specific activity of SNX3, rather than SNX1/SNX6, is involved in retromer-mediated Wg secretion.
Similar(58)
They are simply replaced with another person from the village.
In this case, s is simply replaced with b.
The effects of loading and temperature cannot be simply combined.
Results from studies using standard OVDs cannot be simply extrapolated.
These observations cannot be simply explained by growth promotion.
Physicians, clinicians or family members simply cannot be replaced by machine learning in healthcare".
But, of course, recovery from a disaster that kills a huge number of highly-skilled people cannot be accomplished by simply replacing the dead with newer, more highly-skilled models.
But some things cannot be replaced.
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CEO of Professional Science Editing for Scientists @ prosciediting.com