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Secondary hyperalgesia is the area of hypersensitivity surrounding an injured area that cannot be signaled directly by peripheral sensitization, as the afferents that innervate the secondary area are not sensitized by the injury.
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Furthermore, the SLA Enforcer will drop all traffic flows that belong to a service class for which the requirements cannot be met (signaled by the Admission Control, see Section 4.3.5).
However, when misfolded-protein aggregation persists and ER stress cannot be resolved, signalling switches from a pro-survival to a pro-apoptotic pathway.
In anticipation of future embedded applications where signals are deliberately masked but levels cannot be individualized, signals were standardized at conservative (harder to mask) levels.
Therefore, the comparison cannot be a signal that pervades the whole cell, and instead multipolarity suggests the existence of oriented 'conduits' that link facing regions within the anterior and posterior membranes of a single cell.
If homeostasis cannot be restored, UPR signaling promotes cell death.
Conversantly, if the damage is too severe and ER function cannot be restored, this signaling branch triggers apoptosis.
Therefore, it cannot be excluded that signaling dependent on GSK3β can change, depending on the stage of HD.
Consequently, the possibility cannot be excluded that signalling through one of these occurs in the IFN-γR KO splenocytes.
Photons are wonderfully efficient at hauling data long distances, but their signals cannot be manipulated like electronic signals.
The latter niche role is specific to JAK/STAT signaling in CySCs and cannot be fulfilled by Hh signaling, another CySC self-renewal pathway (Amoyel et al, 2013).
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