Sentence examples for cannot be properly refolded from inspiring English sources

If misfolded proteins cannot be properly refolded, they are targeted for degradation mainly by the ubiquitin-proteasome system.

Denatured proteins that cannot be properly refolded are targeted for degradation by ubiquitination, so it is not surprising that genes involved in protein degradation are induced under heat shock [ 25].

Second, when it becomes clear that a misfolded protein cannot be properly refolded, systems, such as the proteasome, autophagy and ER-associated degradation (ERAD), are deployed to degrade these misfolded proteins (reviewed in Nedelsky et al., 2008; Smith et al., 2011; Varshavsky, 2012).

Another peak, corresponding to monomer (50 kDa), was also clearly seen, indicating that a small amount of denatured protein could not be properly refolded, consistent with the maximal refolding yield at about 70% under current experimental conditions.

They cannot be properly put in context until years later.

Thus the mixtures cannot be properly separated by FastIVA.

Unemployment is so high that it cannot be properly measured.

A measurement result cannot be properly interpreted if not accompanied by its uncertainty.

We have shown that totally ordered systems cannot be properly interconnected in any form.

Thus, the usefulness of the authors' modelling approach cannot be properly assessed.

Buildings and land that cannot be properly protected should be made to withstand flooding.