Your English writing platform
Discover LudwigSuggestions(1)
Exact(17)
NEW ORLEANS, Nov. 22 (AP) — Thousands of federal lawsuits claiming death or injury from the drug Vioxx cannot be pooled into one national class action, a judge ruled Wednesday.
These results indicate that datasets gathered from transects of various lengths cannot be pooled without correction.
Analytically, results from observational studies either cannot be pooled for a meta-analyses or can be done so only with caution.
When financial markets are imperfect, welfare cannot be pooled, and the average individual is not as "representative" as if aggregate consumption could be transferred across real-life individuals.
Furthermore, in the Introduction, it is reported that 'non-invasive imaging of inflammation could be a highly valuable tool as it could help diagnosing many inflammatory conditions, such as osteomyelitis, rheumatoid arthritis, sarcoidosis, inflammatory bowel disease, and fever of unknown origin.' These diseases cannot be pooled together.
In fact, the different effect measures adopted by the Authors to describe the results obtained in different models (ranging from animal in vitro models to randomized clinical trials) cannot be pooled together.
Similar(43)
In practice this means that adverse effects from RCTs, case reports, case series, cohorts, and case controls cannot all be pooled together using standard meta-analysis principles.
Where the heterogeneity cannot be adequately explained, the data will not be pooled in a meta-analysis.
Therefore, the effect of different type of acupuncture on tinnitus should be interpreted apart and cannot be simply pooled altogether in future meta-analysis.
In addition, once individuals have been pooled they cannot be 'unpooled', thus tethering tests of allele frequency differences to the phenotype used for pooling [ 44].
However, pooling leads to the loss of major biological information as it prohibits the assignment of individual genotypes (i.e. genotyping-by-sequencing). Because of this, many biological questions, such as investigating admixture or linking phenotypes with genotypes in studies of natural selection, cannot be addressed when samples are pooled.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com