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There are likely to be fundamental limits on precise individualized genetic risk prediction due to the complex architecture of common traits, including common variants of very small effect, rare variants that cannot be fully enumerated, and complex epistatic interactions, as well as stochastic and possible environmental factors.
Similar(59)
Even though ColiPruned still contains more than 400 reactions, the (1,410,332) elementary modes of this network can be fully enumerated.
"About half of the estimated undercount in New York City was 'within household misses,' " said Arun Peter Lobo, deputy director of the Department of City Planning's population division, "and where the bureau is concerned, that household has been fully enumerated".
Humans cannot be fully hard-wired.
The operation cannot be fully reversed.
-- cannot be fully answered at this time.
It is a large question, and cannot be fully answered.
It cannot be fully interpreted because it contains no dates.
What must be secret cannot be fully democratic.
Might they be efforts to cover a cultural wound whose severity cannot be fully confronted?
Thus, the interference cannot be fully canceled.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com