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In instances where these applications cannot be evaluated with traditional experimental methods, computer simulation provides a flexible approach to evaluation.
Some social scientists, like Lisbeth Schorr of Harvard, have argued that complex, multipronged social interventions cannot be evaluated with scientific treatment and control methods.
However, dynamic quality criteria that have a significant impact on the achievable accuracy and productivity cannot be evaluated with purely algebraic descriptions.
However, if students are only in the laboratory once per week, development time and body mass cannot be evaluated with meaningful precision.
Comparing innovations is challenging because the benefit of different innovations cannot be evaluated with identical criteria.
Gain of energy, in particular of ATP, through the catabolism of carboxylic acids by strain AT cannot be evaluated with certainty.
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e Highest density region Not presented is an analysis of the trichotomous definition of deafness because such a phenotype cannot be evaluated legitimately with the iBay software; the software is limited to the evaluation of binary and normally distributed phenotypes.
This is not to deny that some secondary processes (e.g., awareness of feelings in the generation of behavioral choices) cannot be evaluated in animals with sufficiently clever behavioral learning procedures, as with place-preference procedures and the analysis of changes in learned behaviors after one has induced re-valuation of incentives.
Even in chemotherapy, the drug concentration in one cancer cell is impossible to determine because of tumor heterogeneity; consequently, the true intracellular drug concentration cannot be evaluated in relationship with its efficacy at present.
Since long-term follow-up is difficult in animal models to evaluate normal tissue tolerance in the reirradiation situation, and less severe or more subtle toxicities cannot be evaluated in animal studies especially with the 2 Gy daily PLDR treatment, we used the TBI method and from previous experiments we found 8 Gy to be the suitable dose to show the benefit of PLDR to normal tissues.
Binding of Rfx3 to Abcc8 or voltage-dependent Ca2+ channel genes has not been reported, and although Rfx6 and Rfx3 might coregulate other targets genes, the extent of the functional redundancy of both transcription factors in β cell function and insulin secretion cannot be evaluated, as the phenotype of mice with a deletion of Rfx3 in adult β cells has not been described.
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