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The new sequence has an unusual N-terminal extension of ∼70 residues that cannot be aligned to reference G-proteins and which is characterised by proline-rich repeats.
But she draws and paints in direct response to her own muse and as such cannot be aligned to any particular art movement...... for in common with other maverick artists throughout art history, her work, although bound to no age, is relevant to all.
Inconsistent color patterns cannot be aligned to reference genome and thus are discarded, improving the quality of the aligned colorspace sequences.
These regions cannot be aligned to a fixed structural template, and are left unaligned by Infernal (leading to a multiple alignment whose length is not fixed but may be different in different datasets).
There are 2,420 sequences, of the 30,197 sequences in the combined dataset, that can not be mapped to the genome; 155 sequences have no BLAST alignments to any of the translated genomic open reading frames, 376 sequences have no BLAST alignments that meet the significance requirements, and 1,889 proteins are not mapped because significant portions of the sequences cannot be aligned to the genome.
Unigenes that cannot be aligned to any database were further scanned by ESTScan [ 43].
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MapNext first conducts the unspliced alignment of all query reads, then conducts the spliced alignment of reads that cannot be aligned at the first stage.
Of 88 213 (3.5%) CDS sequences, 3129 were produced by ESTScan program, which cannot to be aligned to known databases.
Thus, we have developed a scanning approach that will find sites in mixed data that can include one or more clades of sequences (each of which can be aligned reliably) as well as sequences which cannot be aligned reliably to any other sequences.
The result is an alternative alignment shown in Fig. 1B, which differs from the hg16 assembly in three major points and is supported by a detailed repeat and SNP/ haplotype analysis: (1) Clones 23 27 not present in the hg16 assembly were located distally of the gap, whereas clones 11, 12 and 17 were excluded since they cannot be aligned according to our criteria.
Therefore, we defined groups within IS families as IS nucleotide sequences that can reliably be aligned to each other within groups but cannot be aligned with sequences from other groups.
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