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These compounds may sever as lead candidates in the development of novel therapeutic drugs for RA treatment.
Electrospun polymeric fibers are attractive candidates in the development of scaffolds for the tissue engineering and for providing new systems for delivery of bioactive molecules.
Collectively, results indicate that aligned electrospun scaffolds and ELP4 coating are promising candidates in the development of biodegradeable vocal fold lamina propria constructs.
The new compounds have been synthesized in only three synthetic steps from cheap building blocks and in high yields, thus turning to be promising drug candidates in the development of cheaper HCV treatments.
These results further strengthen the potential of this novel substance class, being very different to the approved drugs and clinical candidates, in the development of inhibitors less sensitive to drug resistance.
Several identified eQTLs were novel and these implicate genes involved in bone development (IPO8, XYLT1, and PRKAR1A), and ribosomal pathways related to marrow and bone dysfunction, as potential candidates in the development of CMI.
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Its potent activity against antibiotic-resistant bacteria suggests that [K7, P8, K11]-IsCT may serve as a promising lead candidate in the development of new peptide antibiotics.
WSe2 possessed a layered structure with the metal atoms (W) bonded covalently between the layers of chalcogen atoms (Se), and the remarkable feature of the WSe2 was highly antiphotocorrosive due to the observation of layered structure, which made it as a strong candidate in the development of high efficiency photoelectrochemical solar cells [11].
This makes Survivin a leading research candidate in the development of prognostical tool and a prime target in cancer therapy.
Therefore, this compound has potential as a lead candidate in the development of anticancer agents or as an adjunct compound in combination treatment regimes.
Recent studies suggest IL-1β as a putative candidate in the development of insulin resistance and type 2 diabetes (49, 57).
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