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Dr. Lydon sent him several candidate substances, including STI-571.
Many CRM candidate substances have shown serious side effects.
Unfortunately, it was revealed that all candidate substances did not react with Na2CO3 and decomposed before 600 °C.
Thus, various sodium-based compounds were first investigated and three candidate substances satisfying several criteria were selected; sodium bromate (NaBrO3), sodium chlorate (NaClO3), and sodium tetrafluoroborate (NaBF4).
Earth, air, fire, and water were candidate substances in ancient times; energy, the chemical elements, and subatomic particles are more contemporary examples.
It has found a couple of candidate substances - both relatively small molecules that can survive the rigours of the digestive system - and is preparing to begin tests to see which will switch on VEGF production in the body.
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Extracellular ATP is a primary candidate substance of the light peak, an electrophysiological response in the eyes upon light exposure25,26.
Among them, 1- benzofuran-2-yl -2-propylaminopentane BPAP) was selected as a promising candidate substance for further studies.
Specifically, when a firm discovers a new candidate substance for a first in its class drug, how to evaluate the potential risks becomes a key predicament for management.
This agrochemical has been identified as a potential candidate substance for the United Nations Economic Commission for Europe (UN-ECE) Persistent Organic Pollutant (POP) Protocol and implicated as a potential "endocrine disrupting compound".
Through an examination of the processes of drug development related to the same candidate substance in a Japanese firm and an American firm, we suggest that, in addition to organizational capabilities at the corporate level, social capital, specifically formed under a certain innovation system, plays a key role in leading to the successful introduction of breakthrough innovations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com