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RNRdb also contains information about genomes that lack RNRs (determined through candidate screening of complete genome sequences, as described above).
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Alternatively, another class of yet to be identified histone methyltransferases or a methyltransferase that is essential for viability could facilitate placement of this mark, in which case a candidate screen of non-essential ORFs would fail to reveal the responsible enzyme and rather an unbiased approach would have to be employed to identify the catalytic enzyme.
Marker candidate screening involved testing of serum from lung tumour patients and from brain tumour patients as well as control sera under the patients' informed consent.
Meanwhile, for a mere text-mining based candidate screening method, the fraction of retrieved genes relevant to resistance is also low, which means a low recall rate.
(3) A unified workflow for the ranking of multiple candidate screening libraries based on multiple criteria is unavailable.
One promising candidate screening methodology is the identification of outliers by neuroimaging.
To the best of our knowledge, this is the largest study ever which analyses the usefulness of various candidate screening tests for HPAS.
In a recent candidate screen, which consisted of sequencing the coding regions (exons) of 32 candidate genes of 190 CHD patients, a number of novel and potential genetic determinants of atrioventricular valve and septum (AVS) defects were identified.
In addition, specific miRNA levels are altered due to stage of embryonic development and, in the case of miR-24, due to culture conditions, making this miRNA a candidate for screening of embryo quality.
The zebrafish model is an attractive candidate for screening of developmental toxicity during early drug development.
Transcriptional profiles in gills and hemocytes were analyzed upon abalone challenged with viral hemorrhagic septicemia virus (VHSV) in order to select candidates for screening of immune response genes.
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