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Collectively, the data projected Irigenin as a candidate compound for further evaluation.
These results yield new insight into the HCV life cycle and provide a candidate compound for pharmaceutical development.
CIP-A5 has been considered as a candidate compound for treatment of liver cirrhosis.
These data suggest that HSP70-36 may be a potential candidate compound for tumour treatment.
Compound 16 happens to be the candidate compound from this study to investigate further.
Our aim in this study was to evaluate the efficacy of CIP-13F as a candidate compound for cancer treatment.
We and others have reported DZ2002, a reversible SAHH (S-adenosyl-l-homocysteine hydrolase) inhibitor, as a candidate compound for lupus treatment95,96.
In an attempt to solve this problem, the industry is looking for predictive tools that would be useful in testing optimal properties of a candidate compound earlier.
Especially compound 11c was found to be a potent and selective Raf kinase inhibitor and could be considered as a candidate compound for further development.
Moreover, the compound 4a exhibited an acceptable pharmacokinetic profile with bio-availability in rat of 76% and could be considered as a candidate compound for further development.
In addition, the best compound 1a exhibited an acceptable pharmacokinetic profile with bioavailability in rat of 81% and could be considered as a candidate compound for further development.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com