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We then combined fine-mapping, bioinformatics, and bench-based approaches to functionally characterize all candidate causal variants at this locus.
Prior to Darwin, or arguably Lamark, the only candidate causal elaboration was to appeal to God's purposes.
The identify candidate causal SNPs and pathways (ICSNPathway) analysis identified seven candidate SNPs, five genes, and seven pathways, which together revealed seven hypothetical biological mechanisms.
An act's expected utility is a probability-weighted average of its expected utility according to the dependency hypotheses that candidate causal models represent.
Our findings of candidate causal genes may provide expanded insight into mechanisms underlying obesity biology.
Gender neutral, the developmental pathway Dorso-Ventral axis formation may be considered as the candidate causal pathway in chronic pentylenetetrazole induced behavioral deficit.
Amino acid change of candidate causal mutations.
This approach revealed 439 candidate causal variants.
Taken together, both variants remain candidate causal mutations for the observed mutant phenotype.
This suggests a possible mechanism for the candidate causal SNP rs943080.
This filtering revealed 261 candidate causal variants - only two of them were located in coding regions.
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