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Study Design: Patients who were treated for extramammary Paget's disease of the vulva at the University of South Florida were identified in our vulvar cancer database for the period 1988 through 2000.
The Swedish Cancer Register was established in 1958 in order to build a complete cancer database for clinical and epidemiological research purposes.
About 30 rare, deleterious mutations were found in each cell line, with 4-6 found in the COSMIC cancer database for each line.
The new primary breast cancers were found by linking the study cohort with the Finnish Cancer Registry (FCR) database, and these data formed the breast cancer database for the study.
Information on cancer was obtained through linkage with the Swedish Cancer Registry, which was established in 1958 to provide a complete cancer database for clinical and epidemiological research purposes.
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To probe published human breast cancer databases for evidence of genetic patterns suggestive of phospho-PR-driven (SUMO-deficient) lesions, we first defined unique PR gene signatures comprised of genes whose expression was greater in cells expressing KR relative to cells expressing WT receptors (expression > 1.5 fold in KR versus WT, BH adjusted P < 0.01).
For each patient a large number of parameters are entered into the cancer database, but for the purposes of this study attention was confined to the following: age, performance status based on Eastern Cooperative Oncology Group (ECOG), surgical treatment, if any, and adjuvant treatment, that is chemotherapy/radiotherapy.
(C ) The TCGA colon cancer database was analyzed for Daple mRNA expression in 246 colorectal adenocarcinomas.
(G ) The TCGA colon cancer database was analyzed for the relationship between Daple copy number loss and microsatellite status in 461 tumor samples.
After Institutional Review Board IRBB) approval was obtained in Mercy Medical Center in Baltimore, a previously established ovarian cancer database was utilized for this study [ 19].
The death record database was linked and matched with the cancer registration database for identifying cancer deaths and missed cases.
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