Sentence examples for cancer characterized from inspiring English sources
Acute Myeloid Leukemia (AML) is an aggressive blood cancer characterized by high relapse rate and resistance to cytotoxic therapies.
Small cell lung cancer (SCLC) is a neuroendocrine lung cancer characterized by fast growth, early dissemination, and rapid resistance to chemotherapy.
Pancreatic ductaladeno carcinoma (PDAC) is a deadly cancer characterized by multiple molecular alterations, the presence of an intense stroma, poor perfusion, and resistance to therapy.
Here we show that a cell-penetrating peptide, ReACp53, designed to inhibit p53 amyloid formation, rescues p53 function in cancer cell lines and in organoids derived from high-grade serous ovarian carcinomas (HGSOC), an aggressive cancer characterized by ubiquitous p53 mutations.
HNSCC is a complex and aggressive cancer characterized by the emergence of therapy-resistant local and regional recurrences.
We have then extended this strategy to identify compounds that have activity towards cells exhibiting the basal phenotype of breast cancer, a clinically-important breast cancer characterized as ER-, PR-, and Her2- that lacks viable therapeutic options.
Work by us and the National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium (CPTAC; previously the Clinical Proteomic Technology Assessment for Cancer) have published some groundbreaking papers in colorectal, ovarian, breast, and prostate cancer characterizing the genomic, proteomic, and/or phosphoproteomic landscapes in these diseases [15 19].
It is routinely used in staging endometrial and cervical cancer, characterizing adnexal masses, selecting optimal treatment, monitoring treatment and detecting recurrent disease.
Evidence provided suggests that γ-tocotrienol therapy may afford significant benefit in the treatment of breast cancers characterized by Met dysregulation.
Thus, it is hypothesized that a replacement treatment with miR-10a mimics may be a promising strategy for cancers characterized by miR-10a downregulation.
Primary human breast cancers characterized by high vascular density also display elevated levels of GPNMB/OA when compared to those with low vascular density.
