Sentence examples for cancer aggregation from inspiring English sources

In this setting, evident familial cancer aggregation or distinctive personal characteristics are not openly distinguished, and although a generalized cellular or molecular disorder in the entire colorectal mucosa may be suspected, the underlying pathogenic mechanism remains elusive.

Thus, sex-specific models were adjusted by large groups, which is consequently stratification by geographic regions, to evaluate the potential of familial lung cancer aggregation.

This adjustment yielded similar HRs associated with stove change, suggesting that familial lung cancer aggregation is unlikely to explain our results.

We, therefore, adjusted our sex-specific models by group, which is effectively stratification by region and extended families, to determine if our observations may be explained by non-independence of familial lung cancer aggregation.

Moreover, these results are suggestive that future research on the genetic aspects associated with breast cancer development should drive attention to explore the relationships between environmental exposures on carcinogenesis, including familial cancer aggregation.

Genome-wide association studies have identified several genomic regions that are associated with breast cancer risk, but these provide an explanation for only a small fraction of familial breast cancer aggregation.

Factors explaining breast cancer familial aggregation might differ according to age.

We therefore opted to study the role played by P-cadherin in breast cancer cell aggregation and invasion.

MCP is relatively rich in galactose, and antagonizes a binding protein galectin-3 (Gal-3), which results in suppression of cancer cell aggregation, adhesion, and metastasis [ 5, 6].

The third block is dedicated to each compound's associations with age-related pathologies (chronic inflammation, cancer, amyloid aggregation etc).. Compounds and mechanisms were described using multiple chemical and biological databases.

Families showing two or more of these clinical criteria (ie, early age of cancer onset, aggregation of tumours in a sibship, 'verticality', proximal location in the large bowel, multiple primaries) were contacted and the pedigrees extended to second- and third-degree relatives.