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The non-canonical NFκB component p100 can undergo processing when activated [ 18].
Recently, deep sequencing unraveled that tRNA, rRNA, snoRNA, and YRNA can undergo processing into smaller RNA molecules (Rutjes et al., 1999; Rother & Meister, 2011; Sobala & Hutvagner, 2011).
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The purpose of this review is to overview the available information on the development of the freeze-drying process of live, attenuated virus vaccines, herewith focusing on the freezing and drying stresses the viruses can undergo during processing as well as on the mechanisms and strategies (formulation and process) that are used to stabilize them during freeze-drying.
This protein can undergo cotranslational processing to produce a 50 kd protein (p50).
Recent studies demonstrating that GPNMB/OA can undergo proteolytic processing led us to investigate the possibility that this protein was subject to ectodomain shedding in breast cancer cells.
Secreted ADAMTS proteinases can undergo additional processing at their C-terminal end.
Caspase-8 localises to mitochondria in various cell lines, where it can undergo further processing and activation [ 14- 18].
These results indicate that procaspase-9 is functional and can undergo full processing in the presence of additional cytochrome c/dATP.
APP can undergo further processing and full length APP and C-terminal fragments have been localized to neuritic vesicles [ 21, 37].
Schon et al (1993) were able to demonstrate that EpCAM can undergo proteolytic processing and that cleavage may activate EpCAM signalling.
If the multimeric transcript can be made to undergo processing, for example self-processing in the ribozyme case, a large amplification of the DNA sequence into many small RNA copies per transcription event can result.
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