The part of the sentence "can substantially increase" is correct and usable in written English.
You can use the phrase when you want to express that a certain factor can produce a large increase. Example: Investing in professional training for employees can substantially increase productivity.
Even low-dose aspirin can substantially increase the risk of serious gastrointestinal bleeding," said Jacobs.
Reduced input can substantially increase both the mean and variability of population coupling.
More and more evidences suggested that improving photosynthesis can substantially increase crop yields.
However, strategic and coordinated efforts across landscapes or regions can substantially increase the impact and cost-effectiveness of conservation.
A company can substantially increase its resilience by improving its ability to detect — and respond to — disruptions quickly.
The elimination of buried free thiols in FGF-1 can substantially increase the protein half-life in cell culture.
Numerical analyses on both systems reveal that resonance and bistability can substantially increase the systems' average locomotion speed.
Finally, expanding the estimation of benefits to include human capital improvements can substantially increase net inclusive wealth, though calculated benefits vary across the countries.
As a result of their ionic character and their buffering capabilities, weak acids can substantially increase the rate of transport.
Respondent Myriad Genetics, Inc. (Myriad), discovered the precise location and sequence of two human genes, mutations of which can substantially increase the risks of breast and ovarian cancer.
These fixed costs, plus the variable costs of production, must be recovered from sales over the lifetime of the project – and future climate policy can substantially increase the variable costs of these technologies.
