Sentence examples for can positively modulate from inspiring English sources

Specifically, glutamine can positively modulate autophagy through glutaminolysis via the production of ammonia, a positive modulator of autophagy (Table S1I).

Our observations are in line with these results and show that microRNAs miR-17, -20a, and -106b can positively modulate E2F activity despite their direct targeting of E2F1.

However, a truncated member of the Groucho/TLE family, amino terminal enhancer of Split (AES) can positively modulate TCF/LEF-1 activity by antagonizing long Groucho/TLE members in a dominant negative manner.

We have previously reported that eukaryotic elongation factor-2 kinase (eEF-2 kinase, also known as Ca2+/calmodulin-dependent protein kinase III) can positively modulate autophagy and negatively regulate protein synthesis.

Factors which can positively modulate neurogenesis include the release of chemokines, mainly SDf-1α or IFNγ, whereas in contrast, cytotoxic extracellular ATP levels (with consequent ionotropic P2X1 7 and metabotropic P2Y1,2,4,6,11 14 receptor hyperactivation), glutamate or IL1-6 release impede the neurogenic effect.

To provide definitive evidence that mTOR inhibition can positively modulate an immune response, a tumour prevention model was used to isolate the immune effects of combination therapy.

Considering that wild type (WT) TET1 can positively regulate the srGAP3 expression, we wonder whether the TET1 mutants can also modulate the srGAP3 expression.

Previous reports demonstrate that mTOR can be positively modulated by its translocation to the late endosome and lysosome, compartments where Rheb is present and capable of interacting with it [23].

In conclusion, this study showed that Pb infection can be positively modulated by anti-inflammatory therapy with PTX administered at the "early" stages of granulomatous inflammation.

We have also demonstrated that osteoblasts constitutively release nucleotides into the bone microenvironment and that this release can be positively modulated by mechanical loading, supporting a role for the P2X7R in mechanotransduction and subsequent anabolic responses in bone.

Since DHA can modulate glial cell activity, it was considered that dietary supplement of DHA may positively modulate the effects of Alzheimer [109].