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Although composite interval mapping (CIM) and multiple QTL mapping (MQM) can identify multiple QTLs by including additional background markers in the model, these approaches can only precisely locate QTLs with significant main effects and do not detect epistatic QTLs.
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Differently from other approaches that minimize the Euclidean norm and can only handle precisely known systems, the proposed method minimizes a bound to the H2 or H∞ norm of a system that represents the dynamics of the error between the polytopic continuous-time plant and the discrete-time representation.
However, according to present guidelines for patient management, individual treatment outcomes can only be precisely predicted once treatment is initiated on the basis of viral kinetics; a ≥2-Log HCV-RNA) decline at week 12 (early virological response) is the most robust approach for identifying non-responder patients (NPV, 97–100%) and thus constitutes the earliest treatment-stopping rule [4].
Moreover, the duration of deviating episodes can only be precisely taken into account with a reliable and accurate near-continuous glucose sensor.
Potential transcription factor binding sites (TFBS) can only be precisely identified when the true peaks are detected first by "peak calling" tools.
The composite can only be deposited precisely through layer by layer ALD technology.
The magnitude of benefit can only be determined precisely via large randomised-controlled trials with long-term follow-up.
It is more difficult to identify the breakpoint position which can only be mapped precisely in diploid cells.
Not only does the LD50 vary from species to species [ 18] but the qualitative character of the pharmacodynamic action of the drug also is equally varied [ 19]; therefore we can only partially compare precisely the dose and the toxic effects of antiblastic drugs between the model and the human animal model.
By the same token, it can only admit strictly economic motivations, precisely because they can be quantified.
And I can only assume that that is precisely the point, that Milton would – later in 1667 when Paradise Lost is published, he would make his poem canonical just like The Iliad and just like The Odyssey and The Aeneid before anyone had actually read it.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com