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However, according to present guidelines for patient management, individual treatment outcomes can only be precisely predicted once treatment is initiated on the basis of viral kinetics; a ≥2-Log HCV-RNA) decline at week 12 (early virological response) is the most robust approach for identifying non-responder patients (NPV, 97–100%) and thus constitutes the earliest treatment-stopping rule [4].
Moreover, the duration of deviating episodes can only be precisely taken into account with a reliable and accurate near-continuous glucose sensor.
Potential transcription factor binding sites (TFBS) can only be precisely identified when the true peaks are detected first by "peak calling" tools.
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The composite can only be deposited precisely through layer by layer ALD technology.
It is more difficult to identify the breakpoint position which can only be mapped precisely in diploid cells.
The magnitude of benefit can only be determined precisely via large randomised-controlled trials with long-term follow-up.
Consequently, the global dimension of the phenomenon can only be estimated but not precisely defined.
However, primary prevention programs can only be implemented effectively if target groups are precisely defined and their behaviors and characteristics known.
Proximity effect correction can only be accurate if a Point Spread Functions (PSF) is precisely determined.
By contrast where the environment is relatively constant, unbiased estimates of theta can only be obtained if populations are counted precisely.
But Mr Stein explained that monetary policy can be a useful supplement to regulatory measures precisely because those can only be applied to areas of the financial system that are being actively monitored by regulators.
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