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Although MOR desensitization, i.e. the decrease in coupling to native G proteins, is more commonly thought to underlie opioid tolerance and dependence [18], [19] than a switch to Gs coupling, our present data indicate that a decrease in MOR efficacy can not alone mediate chronic opioid effects.
Clearly, population growth can not alone account for the growth in skin cancer diagnoses, an interesting result and one worthy of continued investigation.
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Tamam told Novaya Gazeta that Gulistan had undergone a full range of tests but doctors were yet to determine what was wrong with her: "She is very weak and can not walk alone, tormented by headaches," she said, suggesting that the stress of living at the airport could have been to blame.
They always need to be comforted, they have whims and they can not stay alone for long.
Thus, although genotyping of the p.A31P cMyBP-C mutation can not stand alone in limiting fHCM in MC, it is very important that breeders are aware of the genotype status and breeders should be informed of breeding recommendations.
I still can, but not alone.
It is precisely because now, culturally, we marry for love that you can not expect love alone to carry you.
Nor is America the libertarian paradise of some imaginations, as Charlemagne, a former resident, can attest.Americans are not alone in lamenting EU timidity.
Colleges, however, can not do it alone.
However, government can not solve this alone.
And I CAN, out, but not alone.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com