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I wish there weren't people out there who systematically rape and beat women; I wish there weren't people who induce so much fear in their partners that they can no longer function normally.
Depending on the severity of your depression, you may or may not experience bouts of hopelessness that are so bad that you can no longer function normally or control your emotions.
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You suddenly find that you can no longer function as a normal person.
End-stage renal disease is a condition in which the kidneys no longer function normally.
With the pocket jammed, the protein can no longer function.
Some chambers can no longer function at all.
The I.O.C. suspended Afghanistan's Olympic Committee last fall on the ground that it can no longer function.
The master can no longer function because they've outsourced so much of their life".
In extreme cases it may tilt so far that it can no longer function effectively.
Organs can no longer function, and if heatstroke isn't treated fast, the brain overheats, sometimes leading to death.
The inactive phase is about withdrawal, "the point where you have broken down and can no longer function".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com