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Although the treatment itself can induce allergic reactions, patients who complete the treatment gain protection from the inadvertent, accidental exposure.
Part 2 of this work widens the scope of this approach by investigating a biopharmaceutical product, as the aggregation of peptide based drugs affects their therapeutic activity and can induce allergic reactions in patients.
It is what doctors call a delayed hypersensitivity reaction, more often resulting from application of topical substances, like perfumes, that can induce allergic reactions.
While it can be quite challenging to identify potentially threatening ingredients in packaged foods, it is important to recognize the most common foods that can induce allergic reactions.
Allergenic activity of Del-N11TCTP prompted us to see whether the NH2-terminal truncated TCTP can induce allergic airway inflammation in vivo.
While RrTCTP had no influence on airway inflammation, Del-N11TCTP increased goblet cell hyperplasia in both lung and nasal mucosa, suggesting that NH2-terminal truncated TCTP, rather than full length TCTP, is an active form of TCTP that can induce allergic airway inflammation.
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Cockroach allergen can induce mucosal allergic sensitization and inflammation via PAR-2 (Jeong et al. 2008), induce expression of inflammatory cytokine (e.g., IL-8, IL-6), and trigger innate immune response in the human airway epithelium (Kauffman 2006; Matsumura 2012).
The binding of IgE with antigens causes degranulation of mast cells, which then can induce an allergic reaction.
There are more than 60 000 mite species throughout the world, some of which are well-known sources of allergens that can sensitise humans and induce allergic reactions.
Here, we show that nanosilica particles have the potential to induce allergic immune responses after intranasal exposure.
Other molecules can induce severe systemic allergic reactions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com