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These parameters can, for example, be estimated from consideration of mechanism of action, in vitro potency, pharmacokinetics, protein binding and pharmacodynamic biomarker data.
The parameter λ can, for example, be estimated as λ e = 2 h 2 h 1, which leads to the following estimator of N N Z = ∑ i = 1 T h i 1 − e − 2 h 2 h 1.
The resolution that can be achieved on a given sample with a given setup can for example be estimated by measuring the number of photons collected on a typical image of such sample.
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Russia, for example, is estimated to have spent anywhere from $200 million to $1 billion.
Sub-Saharan Sub-Saharan Africae, is estimated to have tapped less than 8 percent oforts hydropowexamplentisl.
Harmful algal blooms, for example, are estimated to cost the U.S. $82 million or more per year.
In almost all cases, these estimates have excellent age control, the most common example being estimates from marine sediment cores (for example, all boron- and alkenone-based estimates).
This method can for example be used in forensic analysis to estimate donor age of unknown tissue specimen including blood.
The age of DDT, for example, can be estimated from the ratio of the amount of the chemical itself to the amount of its principal breakdown product, DDE.
For example, Sqrt 35) can be estimated to be between 5 and 6 (probably very close to 6).
Third, joint line origin probabilities, required for fitting models of more than one locus per chromosome (for example, in testing for epistasis) can be estimated.
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