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The first three steps involved in the practice of EBM can comprehensively be summarized as a one-page written paper on a particular clinical topic, which is most commonly called a 'Critically Appraised Topic' (CAT) [ 4].
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Due to rapid technical advances in the field of NGS, tumor (including leukemia) genomes can nowadays comprehensively be analyzed within few days.
Under this model, the most cost-effective strategy for fine mapping would focus on assaying coding variation, which can most comprehensively be achieved through whole-exome re-sequencing of cases and controls, and will provide a complete catalogue of protein altering variants across the genome.
The full version of this article, which sets out the required shift in the immigration debate more comprehensively, can be seen in the new Fabian publication Facing the Unknown: Building a Progressive Response to Brexit.
A basic premise of the method is that a variable representing the construct variance comprehensively can be derived from a source other than the construct's measurement vehicle.
Oral well-being can be comprehensively evaluated by the simultaneous application of indicators of oral impacts (OIDP) and oral satisfaction (OSS), because both could be considered major and complementary dimensions of OHRQoL.
The shape distribution of pores can only be comprehensively analyzed using the present method.
The impact of weather on headache can thereby be comprehensively delineated by integrating reports from locations throughout the world.
The F. graminearum genome can now be comprehensively studied with the knowledge that a full set of gene models and surrounding genomic sequence can be probed in combination with non-coding RNA annotation to identify pathogenicity mechanisms.
Such confounding by indication is commonplace throughout clinical research [ 30], including studies of the timing of ART initiation [ 31], and can only be comprehensively addressed through randomized studies [ 32].
It can't be comprehensive; it can only be, as comprehensively as possible, itself.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com