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This gain in efficiency can be substantial especially when there are patients not complying with their assigned treatments.
Testing fees can be substantial, especially when individual genetic variants are assayed sequentially, and indeed are soon likely to rival the cost of obtaining an entire genome sequence.
The costs of multiple medications can be substantial, especially when older patients fall into the "doughnut hole" of Medicare Part D coverage.
The cost of hospitalization due to adverse events associated with rituximab can be substantial, especially when they require an intensive care unit (ICU) admission.
These estimates are also prone to random error, which can be substantial, especially when survival experience between small populations is compared.
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The bias could be substantial especially when data are sparse [ 23, 24].
Unfortunately, your costs can be substantial, especially if you need a lot of health care.
These changes can be substantial, especially for infectious diseases with well-pronounced seasonality [16], [17], [18].
Consequently, the uncertainties can be substantial, especially for the first 2 3 centuries.
"It can be substantial when the market is in turmoil," he said.
The achievements can be substantial when the political will from all stakeholders is in place.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com